Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564248 | 0.73 | KCNN4 (0.40) | KMT2AMEN1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL27476843 | 0.73 | CYP11B1 (0.40) | KMT2AMEN1KDM4EALDH1A1ESR1 | |
| SCHEMBL392779 | 0.71 | CYP11B1 (0.43) | KMT2AMEN1TSHRCYP11B1CYP11B2 | |
| SCHEMBL6720540 | 0.71 | ALDH1A1 (0.35) | KMT2ABACE1MEN1KDM4EHSD17B10 | |
| SCHEMBL20768154 | 0.71 | KMT2A (0.38) | KMT2AMEN1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL23878651 | 0.70 | CES1 (0.38) | KMT2AMEN1KDM4ECYP11B1CYP11B2 | |
| SCHEMBL1564315 | 0.70 | TSHR (0.41) | KMT2AMEN1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6446028 | 0.70 | KMT2A (0.43) | KMT2AMEN1KDM4EESR1CYP11B1 | |
| SCHEMBL7715187 | 0.70 | ALDH1A1 (0.34) | KMT2ABACE1MEN1KDM4EHSD17B10 | |
| SCHEMBL2852162 | 0.70 | KMT2A (0.40) | KMT2AMEN1ESR1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178913-C | Aromatic heterocycle compounds having HIV integrase inhibiting activities | ��Ұ����ҩ��ʽ���� | 2004-12-08 | — | — | CN | disclosed |