⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL29376172 | 1.00 | — | — | |
| Methacrylic Acid SCHEMBL18528878 | 0.82 | — | — | |
| Methacrylic Acid SCHEMBL27351365 | 0.81 | TDP1 (0.52) | — | |
| Methacrylic Acid SCHEMBL10718449 | 0.80 | — | — | |
| Methacrylic Acid SCHEMBL11235035 | 0.78 | TDP1 (0.53) | — | |
| Methacrylic Acid SCHEMBL491341 | 0.78 | TDP1 (0.53) | — | |
| Methacrylic Acid SCHEMBL15043 | 0.78 | TDP1 (0.53) | — | |
| Methacrylic Acid SCHEMBL13234423 | 0.78 | — | — | |
| Methacrylic Acid SCHEMBL15005463 | 0.78 | TDP1 (0.53) | — | |
| Methacrylic Acid SCHEMBL66252 | 0.78 | TDP1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103223189-A | Bone cement in paste form | HERAEUS MEDICAL GMBH | 2013-07-31 | — | — | CN | disclosed |
| CN-102803269-A | Thieno [2,3-B ] pyrimidinedione activators of AMPK and therapeutic uses thereof | POXEL | 2012-11-28 | — | — | CN | disclosed |
| CN-101346366-B | Benzochromene derivatives | MERCK PATENT GMBH | 2012-11-21 | — | — | CN | disclosed |
| CN-102573994-A | Novel bicyclic urea compounds | MERCK PATENT GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-101959879-A | 5-oxo-2 for the treatment and prevention of type 1 and type 2 diabetes | MERCK PATENT GMBH | 2011-01-26 | — | — | CN | disclosed |
| CN-101925596-A | Beta-amino acid derivatives for treatment of diabetes | MERCK PATENT GMBH | 2010-12-22 | — | — | CN | disclosed |
| CN-101827851-A | 5-cyano-thienopyridines for the treatment of tumors | MERCK PATENT GMBH | 2010-09-08 | — | — | CN | disclosed |
| CN-101790519-A | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (s1p) receptor for the treatment of multiple sclerosis | SERONO LAB | 2010-07-28 | — | — | CN | disclosed |
| CN-101189268-B | Oil soluble polymers | EVONIK ROHMAX ADDITIVES GMBH | 2010-07-14 | — | — | CN | disclosed |
| CN-101374800-A | Mandelic hydrazides | MERCK PATENT GMBH (DE) | 2009-02-25 | — | — | CN | disclosed |
| CN-1615297-A | Phenoxy-piperidines for the treatment of schizophrenia and depression | MERCK PATENT GMBH (DE) | 2005-05-11 | — | — | CN | disclosed |
| CN-1582148-A | Derivatives of phenoxy-n-'4-(isothiazolidin-1,1-dioxid-2yl)pheny!-valerian- acid amide and other compounds as inhibitors of the coagulation factor Xa in the treatment of thromboembolic diseases and tu | MERCK PATENT GMBH (DE) | 2005-02-16 | — | — | CN | disclosed |
| CN-1524072-A | Prenyl-containing derivatives and their use in the treatment of thromboembolic disorders or tumours | Ĭ��ר���ɷ�����˾ | 2004-08-25 | — | — | CN | disclosed |
| CN-1514823-A | Oxalic acid derivatives | Ĭ��ר���ɷ�����˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1146563-C | Piperidinylmethyloxazolidinone derivative | Ĭ��ר���ɷ�����˾ | 2004-04-21 | — | — | CN | disclosed |
| CN-1481358-A | Amide derivatives and their use in the treatment of thromboembolic disorders and tumours | Ĭ��ר���ɷ�����˾ | 2004-03-10 | — | — | CN | disclosed |
| CN-1315942-A | 2-oxo-j(2H)-quinoline derivatives | MERCK PATENT GMBH (DE) | 2001-10-03 | — | — | CN | disclosed |
| CN-1272107-A | Benzamidine derivatives as factor Xa inhibitors | MERCK PATENT GMBH (DE) | 2000-11-01 | — | — | CN | disclosed |
| CN-1269799-A | Piperidinylmethyl oxazolidinone derivatives | MERCK PATENT GMBH (DE) | 2000-10-11 | — | — | CN | disclosed |
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |