Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 5/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562420 | 0.84 | GRM5 (0.68) | GRM5 | |
| SCHEMBL2569658 | 0.80 | F2 (0.60) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2551230 | 0.76 | KLK3 (0.52) | MAPTSMN1; SMN2KMT2AGRM5ELANE | |
| SCHEMBL2562097 | 0.76 | KLKB1 (0.57) | MAPTCDK2 | |
| SCHEMBL2569195 | 0.75 | F2 (0.47) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2568165 | 0.75 | F2 (0.60) | MAPTSMN1; SMN2MEN1KMT2AGRM5 | |
| SCHEMBL2564845 | 0.75 | F2 (0.49) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2563531 | 0.75 | F2 (0.59) | MAPTNPC1RAB9AGRM5POLB | |
| SCHEMBL2569541 | 0.75 | F2 (0.52) | MAPTRAB9AMEN1KMT2AGRM5 | |
| SCHEMBL2555846 | 0.75 | F2 (0.57) | MAPTRAB9AMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165482-A | Pyrazole pharmaceutical compositions as protein kinase inhibitors | COR THERAPEUTICS INC (US) | 1997-11-19 | — | — | CN | disclosed |