SCHEMBL2747454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2747906	0.95	EGFR (0.58)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2749939	0.92	EGFR (0.57)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2748749	0.89	ERBB2 (0.60)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2749408	0.88	EGFR (0.58)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2748544	0.86	EGFR (0.61)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2748436	0.85	ERBB2 (0.61)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2748409	0.85	EGFR (0.61)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2749046	0.85	EGFR (0.67)	EGFRERBB2GAKERBB4ERBB3
	SCHEMBL2749186	0.83	EGFR (0.56)	EGFRERBB2GAKERBB4HDAC3
	SCHEMBL2749208	0.83	EGFR (0.56)	EGFRERBB2GAKERBB4ERBB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.