SCHEMBL27474652

SCHEMBL27474652

COC(=O)CNC(=O)c1cc(Cl)c(N)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.59
KDM4E B2RXH2 3/20 0.59
ALDH1A1 P00352 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HPGD P15428 2/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.45
PKM P14618 2/20 0.44
HSD11B1 P28845 2/20 0.43
EGLN1 Q9GZT9 2/20 0.41
VEGFA P15692 1/20 0.41
FLT1 P17948 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
XDH P47989 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10029339 0.83 KDM4E (0.51) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL8743518 0.81 KDM4E (0.56) GAAKDM4EALDH1A1HPGDMAPT
SCHEMBL5631051 0.81 HPGD (0.68) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL4440700 0.80 KDM4E (0.51) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL8957109 0.79 KDM4E (0.61) GAAKDM4EALDH1A1HSD17B10KMT2A
Methylene Chloride SCHEMBL6847367 0.78 HPGD (0.64) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL14712674 0.78 KDM4E (0.53) GAAKDM4EALDH1A1HSD17B10HPGD
SCHEMBL8947267 0.76 KDM4E (0.67) GAAKDM4EALDH1A1HSD17B10KMT2A
SCHEMBL11332390 0.75 KDM4E (0.61) GAAKDM4EALDH1A1MAPTHSD11B1
SCHEMBL8947242 0.75 KMT2A (0.67) GAAKDM4EALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1144521-A Analysis method for testing for traces of beta-agonists and beta-antagonists UNIV GENT (BE) 1997-03-05 CN disclosed