⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27760036 | 0.79 | — | — | |
| SCHEMBL27478534 | 0.79 | — | — | |
| SCHEMBL27950788 | 0.75 | — | — | |
| SCHEMBL27892113 | 0.75 | EGLN1 (0.45) | — | |
| SCHEMBL27606015 | 0.73 | CAMK2A (0.40) | — | |
| SCHEMBL28796526 | 0.71 | SLC22A6 (0.50) | — | |
| SCHEMBL27604492 | 0.71 | AKR1B1 (0.52) | — | |
| SCHEMBL22972019 | 0.69 | — | — | |
| SCHEMBL21753651 | 0.68 | — | — | |
| SCHEMBL5181660 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101213192-B | Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors | IRM LLC | 2012-06-06 | — | — | CN | claimed |
| CN-1960988-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2012-01-25 | — | — | CN | claimed |
| CN-102056933-A | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV | 2011-05-11 | — | — | CN | claimed |
| CN-101648947-A | 4-(n-phenylamino)-quinazolines / quinolines as tyrosine kinase inhibitors | BOEHRINGER INGELHEIM PHARMA DE | 2010-02-17 | — | — | CN | claimed |
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | claimed |
| CN-100546980-C | Benzimidazole derivatives, preparation method and medical application thereof | S BIO PTE LTD (SG) | 2009-10-07 | — | — | CN | claimed |
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | claimed |
| CN-101248041-A | Sphingosine kinase inhibitors | APOGEE BIOTECHNOLOGY CORP (US) | 2008-08-20 | — | — | CN | claimed |
| CN-101213192-A | Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors | IRM LLC (BM) | 2008-07-02 | — | — | CN | claimed |
| CN-100341873-C | Pyrido 2,3-d pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2007-10-10 | — | — | CN | claimed |
| CN-101031568-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2007-09-05 | — | — | CN | claimed |
| CN-1960988-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2007-05-09 | — | — | CN | claimed |
| CN-1860103-A | Benzimidazole derivatives, preparation method and medical application thereof | S BIO PTE LTD (SG) | 2006-11-08 | — | — | CN | claimed |
| CN-1798734-A | Novel compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2006-07-05 | — | — | CN | claimed |
| CN-1768059-A | Pyrido 2,3-d pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2006-05-03 | — | — | CN | claimed |
| CN-1174981-C | Imidazo [1, 2-A ] pyridine and pyrazolo [2, 3-A ] pyridine derivatives | — | 2004-11-10 | — | — | CN | claimed |
| CN-101213192-B | Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors | IRM LLC | 2012-06-06 | — | — | CN | disclosed |
| CN-1960988-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2012-01-25 | — | — | CN | disclosed |
| CN-1509274-A | Metallo proteinase inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1509275-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | disclosed |