Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604492 | 0.86 | AKR1B1 (0.52) | LMNAOR51E2AKR1B1GPR84PPARG | |
| SCHEMBL28796526 | 0.86 | SLC22A6 (0.50) | LMNAOR51E2AKR1B1GPR84PPARG | |
| Butyric Acid SCHEMBL27867181 | 0.81 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27760036 | 0.79 | — | — | |
| Valeric Acid SCHEMBL27867183 | 0.78 | AKR1B1 (0.54) | LMNAOR51E2AKR1B1GPR84PPARG | |
| SCHEMBL27713550 | 0.77 | FFAR3 (0.45) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5407737 | 0.76 | EGLN1 (0.55) | EGLN1LMNAALKBH5SUCNR1FFAR3 | |
| SCHEMBL27950788 | 0.75 | — | — | |
| SCHEMBL27474685 | 0.75 | — | — | |
| Succinic Acid SCHEMBL50511 | 0.74 | FFAR3 (0.77) | EGLN1LMNAALKBH5SUCNR1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102686564-A | Pyrrolidine derivatives | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | disclosed |