Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.64 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.58 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347217 | 1.00 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8824084 | 0.94 | CTSK (0.61) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823891 | 0.92 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823943 | 0.91 | CTSK (0.66) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823894 | 0.91 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL14513408 | 0.87 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823977 | 0.87 | CTSK (0.64) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823892 | 0.87 | CTSK (0.69) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823912 | 0.87 | CTSK (0.65) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL8823951 | 0.86 | CAPN1 (0.63) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177293-A | Method for inhibiting cathepsin K | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | CN | disclosed |