Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | CALML3 | P27482 | 5/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SDHA | P31040 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459662 | 1.00 | MAOA (0.45) | MAOAMAOBCALML3GRM2PTGDR2 | |
| SCHEMBL6965821 | 1.00 | MAOA (0.45) | MAOAMAOBCALML3GRM2PTGDR2 | |
| SCHEMBL6967768 | 0.90 | MAOA (0.49) | MAOAMAOBCALML3F10LMNA | |
| SCHEMBL27458038 | 0.86 | MAOA (0.46) | MAOAMAOBCALML3GRM2PTGDR2 | |
| SCHEMBL6964490 | 0.86 | MAOA (0.46) | MAOAMAOBCALML3GRM2PTGDR2 | |
| SCHEMBL7533913 | 0.85 | MAOA (0.50) | MAOAMAOBCALML3F10LMNA | |
| SCHEMBL6971579 | 0.85 | MAOA (0.50) | MAOAMAOBCALML3F10LMNA | |
| SCHEMBL6964604 | 0.85 | MAOA (0.50) | MAOAMAOBCALML3F10LMNA | |
| SCHEMBL6972790 | 0.84 | MAOA (0.45) | MAOAMAOBCALML3GRM2PTGDR2 | |
| SCHEMBL6956015 | 0.79 | MAOB (0.44) | MAOAMAOBCALML3GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142162-C | Bicyclic oxazolidinones as antibacterial agents | �������Ŷ���Լ��������˾ | 2004-03-17 | — | — | CN | disclosed |
| CN-1353709-A | Bicyclic oxazolidinones as antibacterial agents | PHARMACIA & UP JOHN CO (US) | 2002-06-12 | — | — | CN | disclosed |