SCHEMBL27475337

SCHEMBL27475337

CN(C)c1ccc(PCl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.58
TSHR P16473 6/20 0.58
ALOX15 P16050 4/20 0.58
HSD17B10 Q99714 4/20 0.58
APP P05067 3/20 0.46
MAPK1 P28482 5/20 0.46
CYP3A4 P08684 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 2/20 0.46
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC2A1 P11166 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2A13 Q16696 1/20 0.41
CHRM5 P08912 1/20 0.40
CHKA P35790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL883438 0.78 ALDH1A1 (0.65) ALDH1A1TSHRALOX15HSD17B10APP
SCHEMBL65261 0.76 ALDH1A1 (1.00) ALDH1A1TSHRALOX15HSD17B10APP
SCHEMBL635376 0.76 ALDH1A1 (0.61) ALDH1A1TSHRALOX15HSD17B10APP
SCHEMBL31633568 0.75 ALDH1A1 (0.52) ALDH1A1TSHRALOX15HSD17B10APP
4-Dimethylaminophenol SCHEMBL224308 0.75 APP (0.73) ALDH1A1TSHRALOX15HSD17B10APP
4-Dimethylaminophenol SCHEMBL9792507 0.75 APP (0.73) ALDH1A1TSHRALOX15HSD17B10APP
SCHEMBL11451460 0.74 ALDH1A1 (0.58) ALDH1A1TSHRALOX15HSD17B10APP
Hydrochloric Acid SCHEMBL379125 0.73 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10APP
Hydrochloric Acid SCHEMBL2443748 0.73 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10APP
Hydrochloric Acid SCHEMBL379126 0.73 ALDH1A1 (0.92) ALDH1A1TSHRALOX15HSD17B10APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1165145-A Process for preparing monoalkyl phosphonites HOECHST AG (DE) 1997-11-19 CN claimed