SCHEMBL27475397

SCHEMBL27475397

CC(C)(C)OC(=O)[C@@](C)(N)[C]=O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.43
CTSS P25774 3/20 0.32
CTSK P43235 3/20 0.32
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444101 0.79 DGAT1 (0.41) DGAT1CTSSCTSKCTSLCTSB
SCHEMBL4448260 0.79 DGAT1 (0.41) DGAT1
SCHEMBL4449736 0.79 DGAT1 (0.41) DGAT1
SCHEMBL320271 0.74 DGAT1 (0.50) DGAT1
SCHEMBL27747511 0.74 DGAT1 (0.50) DGAT1
SCHEMBL6687359 0.74 DGAT1 (0.50) DGAT1
SCHEMBL1486198 0.73 DGAT1 (0.44) DGAT1
SCHEMBL27482953 0.73 DGAT1 (0.44) DGAT1
SCHEMBL28535462 0.73 DGAT1 (0.44) DGAT1
SCHEMBL27859821 0.73 DGAT1 (0.44) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1145365-A Camptothecin derivatives TANABE SEIYAKU CO (JP) 1997-03-19 CN disclosed