SCHEMBL27475407

SCHEMBL27475407

CCN(c1nc(C)cc(C)n1)c1cnc(OC)cc1OC

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 18/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7684615 0.76 CRHR1 (0.75) CRHR1
SCHEMBL7684356 0.76 CRHR1 (0.49) CRHR1
SCHEMBL7684974 0.76 CRHR1 (0.63) CRHR1
SCHEMBL7695100 0.75 CRHR1 (0.51) CRHR1
SCHEMBL7687620 0.75 CRHR1 (0.68) CRHR1
SCHEMBL7689380 0.73 CRHR1 (0.65) CRHR1
SCHEMBL7684608 0.72 CRHR1 (0.65) CRHR1
SCHEMBL7684475 0.71 CRHR1 (0.84) CRHR1
SCHEMBL7681108 0.68 CRHR1 (0.58) CRHR1
SCHEMBL7680344 0.68 CRHR1 (0.69) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1142817-A 1N-alkyl-N-arylpyrimidinamines and derivatives thereof DU PONT MERCK PHARMA (US) 1997-02-12 CN disclosed