Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 7/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803644 | 0.81 | CNR2 (0.54) | PSMB8PSMB5POLBCNR2KMT2A | |
| SCHEMBL10827301 | 0.81 | SMN1; SMN2 (0.52) | PSMB5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27478057 | 0.81 | POLB (0.59) | PSMB8PSMB5POLBCNR2KMT2A | |
| SCHEMBL10542964 | 0.81 | POLB (0.59) | PSMB8PSMB5POLBCNR2KMT2A | |
| SCHEMBL21724154 | 0.79 | CNR2 (0.51) | PSMB8PSMB5POLBCNR2KMT2A | |
| SCHEMBL4660369 | 0.78 | CTSK (0.61) | CTSL | |
| SCHEMBL2147583 | 0.78 | CTSK (0.61) | CTSL | |
| SCHEMBL3959352 | 0.78 | CTSK (0.61) | CTSL | |
| SCHEMBL7294138 | 0.78 | POLB (0.56) | PSMB8PSMB5POLBCNR2KMT2A | |
| SCHEMBL2368096 | 0.78 | PSMB8 (0.64) | PSMB8PSMB5POLBCNR2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177293-A | Method for inhibiting cathepsin K | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | CN | disclosed |