Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239404 | 0.87 | GAA (0.55) | STING1EPHX2GAAMEN1KMT2A | |
| SCHEMBL15656106 | 0.87 | MEN1 (0.53) | STING1EPHX2GAAMEN1KMT2A | |
| SCHEMBL8843852 | 0.87 | STING1 (0.43) | STING1EPHX2GAATOP1MEN1 | |
| SCHEMBL21611670 | 0.84 | STING1 (0.54) | STING1EPHX2GAAMEN1KMT2A | |
| SCHEMBL8905338 | 0.81 | EPHX2 (0.56) | STING1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL28279506 | 0.79 | EPHX2 (0.68) | EPHX2FAAHCNR1CNR2 | |
| SCHEMBL26699105 | 0.79 | STING1 (0.48) | STING1EPHX2GAAMEN1KMT2A | |
| SCHEMBL3959551 | 0.79 | TDP1 (0.59) | STING1EPHX2KMT2AHDAC1HDAC2 | |
| SCHEMBL8842303 | 0.79 | MEN1 (0.49) | STING1EPHX2GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8843485 | 0.78 | MEN1 (0.47) | STING1EPHX2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147491-C | Acridine carboxylic ester compound, preparation and medicinal composition thereof | ɪά��ʵ���� | 2004-04-28 | — | — | CN | disclosed |