Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179770 | 0.74 | GHSR (0.42) | GHSROPRM1OPRL1SLC6A4SLC6A3 | |
| SCHEMBL27524197 | 0.73 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL27551451 | 0.67 | MEN1 (0.35) | GHSROPRM1SLC6A4 | |
| SCHEMBL7851148 | 0.66 | GHSR (0.56) | GHSROPRM1OPRL1 | |
| SCHEMBL6176208 | 0.65 | GHSR (0.77) | GHSR | |
| SCHEMBL12164925 | 0.61 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14156408 | 0.60 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL26208919 | 0.59 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17220992 | 0.57 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7321869 | 0.57 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161333-C | Oxindole derivatives as growth hormone releasers | ס����ҩ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1313853-A | Oxindole derivatives as growth hormone releasers | SUMITOMO PHARMA (JP) | 2001-09-19 | — | — | CN | disclosed |