Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | FPR2 | P25090 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606056 | 0.89 | EPHX1 (0.81) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4797277 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2KDM4ECA2 | |
| SCHEMBL4898196 | 0.81 | KMT2A (0.81) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL10192078 | 0.81 | ALDH1A1 (0.83) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4897395 | 0.81 | CNR1 (0.74) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4894746 | 0.81 | CNR1 (1.00) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL5516178 | 0.81 | CNR1 (0.73) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL16857481 | 0.81 | CNR1 (0.73) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL14280558 | 0.81 | CNR1 (0.76) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL4637408 | 0.80 | CNR1 (0.71) | CNR1NPC1RAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149869-A | Substituted sulfonamides as selective beta3 agonists for treatment of diabetes and obesity | MERCK & CO LTD (US) | 1997-05-14 | — | — | CN | disclosed |