Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.45 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385244 | 0.86 | HPGD (0.47) | EPHX1GPR119HPGDDPP4RECQL | |
| SCHEMBL7299583 | 0.82 | HPGD (0.46) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL12211462 | 0.81 | EPHX1 (0.55) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL16508861 | 0.81 | EPHX1 (0.48) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL19455003 | 0.80 | HPGD (0.49) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL3821259 | 0.80 | EPHX1 (0.54) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL3640119 | 0.79 | DPP4 (0.53) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL15925038 | 0.79 | EPHX1 (0.49) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL903630 | 0.79 | DPP4 (0.53) | EPHX1GPR119EEDRBBP4SUZ12 | |
| SCHEMBL27544930 | 0.79 | EPHX1 (0.49) | EPHX1GPR119EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131665-A | Piperazine derivatives, medicaments comprising these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1996-09-25 | — | — | CN | disclosed |