SCHEMBL27476158

SCHEMBL27476158

CC(=O)C(COc1ccccc1)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.52
CYP1A2 P05177 1/20 0.52
MTNR1A P48039 3/20 0.51
MTNR1B P49286 3/20 0.51
LMNA P02545 1/20 0.49
CPA1 P15085 2/20 0.46
CPA3 P15088 2/20 0.46
FOLH1 Q04609 1/20 0.46
CPB1 P15086 1/20 0.46
CPB2 Q96IY4 1/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10983129 0.86 CYP1A2 (0.66) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL497369 0.82 CYP1A2 (0.68) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL27868779 0.81 MTNR1A (0.53) MMEMTNR1AMTNR1BLMNACPA1
SCHEMBL4724923 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL28912638 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL4451600 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL29865739 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL107422 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL2588080 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1
SCHEMBL40705 0.80 CYP1A2 (0.65) MMECYP1A2CPA1CPA3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101792380-A Novel method for synthesizing P-methoxy phenylacetone by using fennel oil UNIV NORTHWEST NATIONALITIES 2010-08-04 CN claimed
CN-101544552-B Method for synthesizing p- hydroxyphenylacetone CHANGZHOU RUIMING PHARMACEUTICAL CO LTD 2012-05-30 CN disclosed
CN-101792380-A Novel method for synthesizing P-methoxy phenylacetone by using fennel oil UNIV NORTHWEST NATIONALITIES 2010-08-04 CN disclosed
CN-100579958-C Racemized tamsulosin free alkali and preparation method thereof SYNTHON BV 2010-01-13 CN disclosed
CN-101544552-A Synthesis method of medical midbodies of para(ortho)-hydroxybenzoic acetone CHANGZHOU RUIMING PHARMACEUTIC 2009-09-30 CN disclosed
CN-100343227-C Process for resolution of tamsulosin SYNTHON BV (NL) 2007-10-17 CN disclosed
CN-1578761-A Process for resolution of tamsulosin SYNTHON BV (NL) 2005-02-09 CN disclosed
CN-1578762-A Racemic tamsulosin free base and process for preparing same SYNTHON BV (NL) 2005-02-09 CN disclosed
CN-1147562-C Liquid-crystalline polyethers 德吉玛泰克有限公司 2004-04-28 CN disclosed
CN-1157631-A Liquid-crystalline glasses AKZO NOBEL NV (NL) 1997-08-20 CN disclosed
CN-1157004-A Liquid-crystalline polyethers AKZO NOBEL NV (NL) 1997-08-13 CN disclosed