Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20712075 | 1.00 | POLB (0.50) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL3096440 | 1.00 | POLB (0.50) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL3096445 | 1.00 | POLB (0.50) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL8176908 | 0.87 | POLB (0.46) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL16808494 | 0.83 | TSHR (0.44) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL16808624 | 0.83 | TSHR (0.44) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL18186731 | 0.83 | TSHR (0.44) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL28365208 | 0.83 | TSHR (0.44) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL28364992 | 0.83 | TSHR (0.44) | POLBTSHRCYP2D6ALDH1A1MAPT | |
| SCHEMBL487564 | 0.83 | TSHR (0.67) | POLBTSHRCYP2D6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663029-A | DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS | XEROX CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| US-8178474-B1 | Functionalised solid support for alpha-oxoaldehyde synthesis | INSTITUT PASTEUR DE LILLE (FR) | 2012-05-15 | — | — | US | disclosed |
| US-5199450-A | SMOKING COMPOSITIONS CONTAINING A TARTRATE SALT FLAVORANT-RELEASE ADDITIVE | PHILIP MORRIS INCORPORATED (US) | 1993-04-06 | — | — | US | disclosed |