Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 3/20 | 0.53 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.53 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761503 | 0.88 | MLLT1 (0.61) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL27462593 | 0.87 | KDM4E (0.60) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL6164864 | 0.85 | PYGL (0.65) | FLT3PYGLSMYD3RXFP1 | |
| SCHEMBL24380183 | 0.81 | KDM4E (0.55) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL2735811 | 0.81 | PYGL (0.56) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL24196808 | 0.80 | FLT3 (0.60) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL17149666 | 0.79 | PYGL (0.60) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL17149890 | 0.79 | PYGL (0.60) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL2735810 | 0.79 | PYGL (0.57) | FLT3KDM4EALDH1A1PDPK1LMNA | |
| SCHEMBL17149882 | 0.79 | PYGL (0.60) | FLT3KDM4EALDH1A1PDPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142492-A | Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents | PFIZER (US) | 1997-02-12 | — | — | CN | disclosed |