SCHEMBL27477995

SCHEMBL27477995

O=CC(=O)OF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1252113 0.74 HCAR2 (0.44)
SCHEMBL14690128 0.74 HCAR2 (0.44)
SCHEMBL7611159 0.69
SCHEMBL425800 0.69
SCHEMBL27844936 0.67
SCHEMBL28202358 0.67
SCHEMBL9479022 0.67
Methane SCHEMBL9232564 0.67
Hydrochloric Acid SCHEMBL27825877 0.67
SCHEMBL28674601 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1616432-A Compound,its use and pharmaceutical compositions comprising same ELAN PHARM INC (US) 2005-05-18 CN disclosed
CN-1171878-C Compounds, their use and pharmaceutical compositions containing them ������˹ҩƷ��˾ 2004-10-20 CN disclosed
CN-1242007-A Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds ELAND PHARMACEUTICAL CORP (US) 2000-01-19 CN disclosed