Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252113 | 1.00 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2ATM | |
| SCHEMBL27934007 | 0.87 | — | — | |
| SCHEMBL11223859 | 0.83 | — | — | |
| SCHEMBL27480835 | 0.81 | — | — | |
| SCHEMBL27520850 | 0.81 | — | — | |
| SCHEMBL28179973 | 0.81 | KEAP1 (0.32) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL8900190 | 0.76 | — | — | |
| SCHEMBL27306780 | 0.76 | — | — | |
| SCHEMBL27477995 | 0.74 | — | — | |
| SCHEMBL425800 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483194-A | 2-fuloro fumarate (formula I), and preparation method and application thereof | YANG YINKE | 2014-01-01 | — | — | CN | claimed |
| CN-106030309-B | Universal antigen retrieval compounds and methods of use thereof | 休斯敦大学系统 | 2019-11-26 | — | — | CN | disclosed |
| CN-106030309-A | Universal antigen retrieval compounds and methods of use thereof | 休斯敦大学系统 | 2016-10-12 | — | — | CN | disclosed |
| CN-103483194-B | A kind of 2-fluoro fumarate (structural formula I) and preparation method thereof and application | YANG YINKE (CN) | 2016-03-09 | — | — | CN | disclosed |
| US-20150196585-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-16 | — | — | US | disclosed |
| US-20150183908-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-02 | — | — | US | disclosed |
| EP-2874633-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | Relypsa, Inc. (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8884093-B2 | Method of treating effluents containing halogenated compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-11-11 | — | — | US | disclosed |
| WO-2014015240-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
| WO-2014015244-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
| CN-103483194-A | 2-fuloro fumarate (formula I), and preparation method and application thereof | YANG YINKE | 2014-01-01 | — | — | CN | disclosed |
| US-20130041200-A1 | METHOD OF TREATING EFFLUENTS CONTAINING HALOGENATED COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183908-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | PICALM, ORAI1, KCNN3 | HCAR2 471/4885KEAP1 3452/4885NFE2L2 4531/4885 |
| US-20150196585-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | SSB, PARG, HLA-DRB1 | HCAR2 978/4885KEAP1 2029/4885NFE2L2 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.