SCHEMBL27478144

SCHEMBL27478144

[CH2]C(COC)CN(C(N)=O)c1ccccc1.[H+]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX5 P09917 1/20 0.33
CHRNB2 P17787 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27495427 0.84 ALDH1A1 (0.46) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL27478564 0.82 HTT (0.42) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL28632800 0.75 ALDH1A1 (0.48) TSHRALDH1A1GLASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL27494938 0.73 ALDH1A1 (0.47) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL609514 0.70 ALDH1A1 (0.43) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL1382126 0.70 CYP3A4 (0.41) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL28294373 0.69 ALDH1A1 (0.46) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL340272 0.69 ALDH1A1 (0.70) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL1416009 0.69 ALDH1A1 (0.48) TSHRALDH1A1GLASMN1; SMN2MEN1
SCHEMBL10526462 0.69 ALDH1A1 (0.52) TSHRALDH1A1GLASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1192015-C Cell adhesion inhibitors BIOGEN INC (US) 2005-03-09 CN disclosed
CN-1177343-A Cell adhesion inhibitors BIOGEN INC (US) 1998-03-25 CN disclosed