SCHEMBL27478422

SCHEMBL27478422

O=C(O)c1ccc2nc(CN3CCCCC3)n(CC3CCC3)c2c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27478667 0.88 GLP1R (0.48) GLP1R
SCHEMBL27477841 0.87 GLP1R (0.58) GLP1R
SCHEMBL24793851 0.86 GLP1R (0.59) GLP1R
SCHEMBL27478630 0.85 GLP1R (0.60) GLP1R
SCHEMBL27479028 0.84 GLP1R (0.45) GLP1R
SCHEMBL27479173 0.81 GLP1R (0.53) GLP1R
SCHEMBL27479094 0.79 GLP1R (0.51) GLP1R
SCHEMBL27479077 0.79 GLP1R (0.51) GLP1R
SCHEMBL29826147 0.77 GLP1R (0.58) GLP1R
SCHEMBL25089540 0.77 GLP1R (0.58) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026338-A1 N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. (US) 2024-02-01 — — WO disclosed
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