Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477879 | 0.88 | GLP1R (0.50) | GLP1RKCNH2 | |
| SCHEMBL27478422 | 0.88 | GLP1R (0.57) | GLP1R | |
| SCHEMBL24791812 | 0.87 | GLP1R (0.51) | GLP1RKCNH2 | |
| SCHEMBL27479069 | 0.87 | MC4R (0.43) | GLP1RHDAC6MLLT1MC4RALDH1A1 | |
| SCHEMBL23046843 | 0.85 | ACSS2 (0.44) | GLP1RCNR2ALDH1A1NPSR1CNR1 | |
| SCHEMBL27478604 | 0.79 | MC4R (0.45) | GLP1RHDAC6MLLT1MC4RALDH1A1 | |
| SCHEMBL29103527 | 0.79 | GLP1R (0.50) | GLP1RKCNH2 | |
| SCHEMBL29103523 | 0.79 | GLP1R (0.50) | GLP1RKCNH2 | |
| SCHEMBL29826354 | 0.79 | GLP1R (0.50) | GLP1RKCNH2 | |
| SCHEMBL27477841 | 0.76 | GLP1R (0.58) | GLP1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |