Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | PPARD | Q03181 | 6/20 | 0.58 |
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28248018 | 0.96 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL27937400 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL27824860 | 0.92 | SLC22A6 (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28191617 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2244299 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL25482 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL4930 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1330953 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28191616 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117364107-A | Off-site electrocatalytic reaction method and reaction system | 中国科学院大连化学物理研究所 | 2024-01-09 | — | — | CN | disclosed |
| CN-106832262-B | With the nano combined nylon material and preparation method thereof for exempting to spray high optical property | 上海跃贝新材料科技股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106832262-A | With nano combined nylon material for exempting to spray optical property high and preparation method thereof | 上海跃贝塑化科技有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-106085201-A | A kind of graphene oxide electrically-conducting paint and preparation method thereof | 代长华 | 2016-11-09 | — | — | CN | disclosed |
| CN-102380301-A | Limestone-plaster wet method flue gas desulfurization composite synergistic agent | XI AN THERMAL POWER RES INST | 2012-03-21 | — | — | CN | disclosed |
| CN-1151719-C | Disinfectant | 日华化学株式会社 | 2004-06-02 | — | — | CN | disclosed |
| CN-1177441-A | Disinfectant | NIPPON PEROXIDE CO LTD (JP) | 1998-04-01 | — | — | CN | disclosed |