SCHEMBL27480537

SCHEMBL27480537

CCC[CH]Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
IDO1 P14902 4/20 0.41
CYP3A4 P08684 3/20 0.39
MAOB P27338 1/20 0.38
ALDH1A1 P00352 2/20 0.38
PYCR1 P32322 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
KMT2A Q03164 2/20 0.36
KIF11 P52732 1/20 0.36
MIF P14174 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140754 0.84 TAAR1 (0.45) TAAR1IDO1MAOBALDH1A1PYCR1
SCHEMBL9428626 0.82 TSHR (0.42) BCHEACHETSHR
SCHEMBL27456003 0.79 HTR2A (0.50) TAAR1IDO1MAOBALDH1A1KDM4E
SCHEMBL27453414 0.78 TRPA1 (0.46) TAAR1IDO1ALDH1A1
SCHEMBL9069769 0.77 TP53 (0.40) TAAR1IDO1ALDH1A1KDM4ECYP2C9
SCHEMBL2093819 0.77 TSHR (0.46) ALDH1A1BCHEACHETSHR
SCHEMBL27456000 0.75 IDO1 (0.41) TAAR1IDO1ALDH1A1ACHECYP1A2
SCHEMBL3168435 0.75 TAAR1 (0.48) TAAR1IDO1MAOBALDH1A1PYCR1
SCHEMBL3984962 0.74 CYP3A4 (0.43) CYP3A4ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL11571963 0.74 CYP3A4 (0.35) IDO1CYP3A4PYCR1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1110486-C Substituted 2-amino-4-alkylamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-06-04 CN disclosed
CN-1239956-A Substituted 2-amino-4-alkylamino-1,3,5-triazines as herbicides BAYER AG (DE) 1999-12-29 CN disclosed