⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458063 | 0.65 | — | — | |
| SCHEMBL622942 | 0.60 | — | — | |
| SCHEMBL6415559 | 0.59 | — | — | |
| SCHEMBL2097314 | 0.52 | PTK2 (0.47) | — | |
| Hydrochloric Acid SCHEMBL2097351 | 0.50 | PTK2 (0.44) | — | |
| SCHEMBL11834 | 0.50 | — | — | |
| SCHEMBL8601412 | 0.49 | TSHR (0.33) | — | |
| SCHEMBL15926028 | 0.48 | POLB (0.37) | — | |
| SCHEMBL6568058 | 0.48 | POLB (0.37) | — | |
| SCHEMBL14308323 | 0.46 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626030-B2 | Compounds and methods of use | AMGEN INC. (US) | 2009-12-01 | — | — | US | claimed |
| US-7435823-B2 | Compounds and methods of use | AMGEN INC. (US) | 2008-10-14 | — | — | US | claimed |
| JP-2007518823-A | — | — | 2007-07-12 | — | — | JP | claimed |
| JP-2007518824-A | — | — | 2007-07-12 | — | — | JP | claimed |
| CN-1933839-A | Compounds and methods of use | AMGEN INC (US) | 2007-03-21 | — | — | CN | claimed |
| US-20060241115-A1 | Compounds and methods of use | AMGEN INC. | 2006-10-26 | — | — | US | claimed |
| EP-1713484-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1711495-A2 | QUINOLINE, QUINAZOLINE, PYRIDINE AND PYRIMIDINE COUNDS AND THEIR USE IN THE TREATMENT OF INFLAMMATION, ANGIOGENESIS AND CANCER | AMGEN INC. (US) | 2006-10-18 | — | — | EP | claimed |
| US-20050245547-A1 | 6-((6,7-Bis(methoxy)-4-quinolinyl)oxy)-N-(3-methylphenyl)-1-benzofuran-3-carboxamide;antiproliferative; -metastasis; -carcinogenic; -tumor; -inflammatory; -arthritic agents;hypotensive agents; myocardium necrosis; rheumatic diseases; tyrosine kinase inhibitors; antiallergens; asthma | AMGEN INC. | 2005-11-03 | — | — | US | claimed |
| WO-2005073224-A2 | QUINOLINE QUINAZOLINE PYRIDINE AND PYRIMIDINE COUNDS AND THEIR USE IN THE TREATMENT OF INFLAMMATION ANGIOGENESIS AND CANCER | AMGEN INC (US) | 2005-08-11 | — | — | WO | claimed |
| WO-2005070891-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2005-08-04 | — | — | WO | claimed |
| US-11358957-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-06-14 | — | — | US | disclosed |
| US-20200277287-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-03 | — | — | US | disclosed |
| US-8178557-B2 | Compounds and methods of use | AMGEN INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-7626030-B2 | Compounds and methods of use | AMGEN INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20050038059-A1 | Thiazolyl substituted aminopyrimidines as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2005-02-17 | — | — | US | disclosed |
| EP-1455579-A1 | PYRAZOLES-PYRIMIDINE FUNGICIDES | Syngenta Participations AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| EP-1434776-A1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | Syngenta Participations AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003049542-A1 | PYRAZOLES-PYRIMIDINE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-19 | — | — | WO | disclosed |
| WO-2003029249-A1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-10 | — | — | WO | disclosed |