Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | SCN4A | P35499 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450360 | 1.00 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19L3MBTL1TSHR | |
| SCHEMBL5469848 | 0.84 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19L3MBTL1TACR1 | |
| SCHEMBL5460913 | 0.84 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19L3MBTL1TACR1 | |
| SCHEMBL93693 | 0.79 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP2C19TSHRMAPK1 | |
| SCHEMBL7619003 | 0.79 | SLC6A4 (0.57) | CYP1A2CYP2D6CYP2C19L3MBTL1TSHR | |
| SCHEMBL14169041 | 0.79 | SLC6A4 (0.57) | CYP1A2CYP2D6CYP2C19L3MBTL1TSHR | |
| SCHEMBL23774519 | 0.78 | L3MBTL1 (0.45) | L3MBTL1TSHRMAPK1ATMTDP1 | |
| SCHEMBL4578371 | 0.78 | AOC3 (0.44) | CYP1A2CYP2D6CYP2C19SCN4ASLC6A4 | |
| SCHEMBL7770297 | 0.78 | CYP1A2 (0.63) | CYP1A2CYP2D6CYP2C19L3MBTL1TSHR | |
| SCHEMBL8470594 | 0.78 | ESR1 (0.43) | CYP1A2CYP2D6CYP2C19TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167692-C | Aminothiazole derivatives and their use as CRF receptor ligands | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1370154-A | Aminothiazole derivatives and their use as CRF receptor ligands | SANOFI SYNTHELABO (FR) | 2002-09-18 | — | — | CN | disclosed |