Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL29172594 | 0.90 | CYP4F2 (0.68) | CYP4F2CYP4A11CYP4Z1EPHX2FFAR1 | |
| SCHEMBL2293786 | 0.89 | CYP4F2 (0.72) | CYP4F2CYP4A11CYP4Z1FFAR1FFAR4 | |
| Trifluoroacetic Acid SCHEMBL27561830 | 0.84 | L3MBTL1 (0.47) | CYP4F2CYP4A11EPHX2FFAR1FFAR4 | |
| SCHEMBL18011670 | 0.82 | CYP4F2 (0.62) | CYP4F2CYP4A11CYP4Z1FFAR1FFAR4 | |
| Trifluoroacetic Acid SCHEMBL27529274 | 0.81 | FFAR1 (0.61) | FFAR1FFAR4IDO1 | |
| SCHEMBL1587300 | 0.81 | CYP4F2 (0.74) | CYP4F2CYP4A11CYP4Z1FFAR1TDP1 | |
| SCHEMBL68902 | 0.81 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1EPHX2TDP1 | |
| SCHEMBL2291044 | 0.80 | CYP4F2 (0.58) | CYP4F2CYP4A11CYP4Z1TDP1KMT2A | |
| SCHEMBL5646521 | 0.79 | CYP4F2 (0.66) | CYP4F2CYP4A11CYP4Z1EPHX2FFAR1 | |
| Hydrochloric Acid SCHEMBL27739628 | 0.78 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1EPHX2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | disclosed |