Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.45 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221196 | 1.00 | LPAR3 (0.46) | LPAR3LPAR1LPAR2PLA2G2CPLA2G2D | |
| SCHEMBL28047672 | 1.00 | LPAR3 (0.46) | LPAR3LPAR1LPAR2PLA2G2CPLA2G2D | |
| SCHEMBL27717633 | 0.91 | LPAR1 (0.52) | LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL28211136 | 0.82 | LPAR3 (0.47) | LPAR3LPAR1LPAR2ENPP2LPAR6 | |
| SCHEMBL26927591 | 0.82 | LMNA (0.55) | — | |
| SCHEMBL27929979 | 0.82 | LMNA (0.55) | — | |
| SCHEMBL3624757 | 0.80 | LPAR3 (0.62) | LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL3620347 | 0.80 | LPAR3 (0.62) | LPAR3LPAR1LPAR2ENPP2 | |
| SCHEMBL3624764 | 0.80 | LPAR3 (0.59) | LPAR3LPAR1LPAR2ENPP2 | |
| Stearic Acid SCHEMBL30585144 | 0.79 | LPAR3 (0.58) | LPAR3LPAR1LPAR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520409-A | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX INC | 2019-11-29 | — | — | CN | claimed |
| CN-110352071-A | Lipidic nanoparticles mRNA vaccine | 库瑞瓦格股份公司 | 2019-10-18 | — | — | CN | claimed |
| CN-105848479-B | Prostacyclin compounds, compositions and methods of use thereof | 英斯梅德股份有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-105934240-A | Hybrid, composition containing the hybrid, preparation method and use thereof | 安杰瑞姆生物科学公司 | 2016-09-07 | — | — | CN | claimed |
| CN-105848479-A | Prostacyclin compounds, compositions and methods of use thereof | 英斯梅德股份有限公司 | 2016-08-10 | — | — | CN | claimed |
| CN-102973506-B | Cationic liposome and preparation method thereof | SHENZHEN INST OF ADV TECH CAS | 2015-06-03 | — | — | CN | claimed |
| CN-102973506-A | Cationic liposome and preparation method thereof | SHENZHEN INST OF ADV TECH CAS | 2013-03-20 | — | — | CN | claimed |
| CN-102068698-A | Nanometer vaccine and preparation method thereof | SHENZHEN INST OF ADV TECH CAS | 2011-05-25 | — | — | CN | claimed |
| CN-1167461-C | Carbon dioxide enhancement of inhalation therapy | �������о�����չ˽������˾ | 2004-09-22 | — | — | CN | claimed |
| CN-1424914-A | Carbon dioxide enhancement of inhalation therapy | RES DEV FOUNDATION (US) | 2003-06-18 | — | — | CN | claimed |
| CN-110520409-A | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX INC | 2019-11-29 | — | — | CN | disclosed |
| CN-105814205-B | Complement component iRNA composition and its application method | 阿尔尼拉姆医药品有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-105813721-B | Device for dispensing particles in small volumes | 不列颠哥伦比亚大学 | 2019-11-05 | — | — | CN | disclosed |
| CN-110392577-A | RNA vaccines and immune checkpoint inhibitors for combination anti-cancer therapy | 库尔维科公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110381994-A | Nucleoside modified RNA for inducing immune response against Zika virus | 宾夕法尼亚大学理事会 | 2019-10-25 | — | — | CN | disclosed |
| CN-101854918-A | Nucleic acid complex and nucleic acid delivery composition | OTSUKA PHARMA CO LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-101646443-A | Prompt nucleic acid delivery carrier composition | TAKEUCHI HIROFUMI JP | 2010-02-10 | — | — | CN | disclosed |
| CN-101291678-A | Carrier composition for nucleic acid transfer | OTSUKA PHARMA CO LTD (JP) | 2008-10-22 | — | — | CN | disclosed |
| CN-1167461-C | Carbon dioxide enhancement of inhalation therapy | �������о�����չ˽������˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1424914-A | Carbon dioxide enhancement of inhalation therapy | RES DEV FOUNDATION (US) | 2003-06-18 | — | — | CN | disclosed |