Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485938 | 0.86 | PRKCI (0.53) | MAPTSMN1; SMN2KDRLMNACYP17A1 | |
| SCHEMBL27484538 | 0.84 | CYP17A1 (0.56) | MAPTSMN1; SMN2KDRLMNAHTT | |
| SCHEMBL27468045 | 0.83 | KDR (0.44) | MAPTSMN1; SMN2KDRLMNAHTT | |
| SCHEMBL27486254 | 0.82 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2KDRLMNAHTT | |
| SCHEMBL27548625 | 0.82 | KDR (0.59) | MAPTSMN1; SMN2KDRALDH1A1KMT2A | |
| SCHEMBL27465575 | 0.82 | P2RX1 (0.50) | MAPTSMN1; SMN2KDRLMNAHTT | |
| SCHEMBL27519714 | 0.81 | MEN1 (0.51) | MAPTSMN1; SMN2KDRLMNAALDH1A1 | |
| SCHEMBL27508410 | 0.81 | KCNK3 (0.45) | MAPTSMN1; SMN2KDRLMNAALDH1A1 | |
| SCHEMBL27466657 | 0.79 | PTGS1 (0.64) | KDRGAAKMT2AMAPK1 | |
| SCHEMBL27485596 | 0.79 | KCNK3 (0.49) | MAPTSMN1; SMN2KDRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | claimed |
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |