Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PRKCI | P41743 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TYK2 | P29597 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467102 | 0.90 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTPRKCIHTTKDM4E | |
| SCHEMBL27485248 | 0.90 | KDR (0.59) | SMN1; SMN2MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL27486256 | 0.89 | KDR (0.57) | SMN1; SMN2MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27609433 | 0.89 | ALDH1A1 (0.52) | SMN1; SMN2MAPTPRKCIHTTKDM4E | |
| SCHEMBL27485596 | 0.89 | KCNK3 (0.49) | SMN1; SMN2MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL27468045 | 0.88 | KDR (0.44) | SMN1; SMN2MAPTPRKCIHTTKDM4E | |
| SCHEMBL27484538 | 0.87 | CYP17A1 (0.56) | SMN1; SMN2MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL27548625 | 0.87 | KDR (0.59) | SMN1; SMN2MAPTALDH1A1JAK1KDR | |
| SCHEMBL27485938 | 0.87 | PRKCI (0.53) | SMN1; SMN2MAPTPRKCILMNAKDR | |
| SCHEMBL27465575 | 0.87 | P2RX1 (0.50) | SMN1; SMN2MAPTPRKCIHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | claimed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | claimed |
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |