Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 13/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 13/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4974383 | 0.91 | KDR (0.58) | ADRA2CTYK2FLT1NAMPTLMNA | |
| SCHEMBL4976745 | 0.89 | KDR (0.59) | ADRA2CTYK2FLT1NAMPTLMNA | |
| SCHEMBL27467101 | 0.82 | KDR (0.67) | FLT1KDRABL1EGFRCSF1R | |
| SCHEMBL1715510 | 0.79 | ADRA2C (0.63) | ADRA2CNAMPT | |
| SCHEMBL4978331 | 0.77 | KDR (0.61) | TYK2FLT1NAMPTKDR | |
| SCHEMBL1715367 | 0.76 | ADRA2C (0.53) | ADRA2CFLT1NAMPT | |
| SCHEMBL27554072 | 0.75 | PLG (0.50) | TYK2 | |
| SCHEMBL4979677 | 0.74 | KDR (0.71) | ADRA2CTYK2FLT1NAMPTKDR | |
| SCHEMBL27485937 | 0.73 | KDR (0.70) | FLT1KDRABL1EGFRCSF1R | |
| SCHEMBL27824623 | 0.72 | PLG (0.47) | TYK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | claimed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | claimed |
| CN-1152014-C | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | ��˹��ŵ�� | 2004-06-02 | — | — | CN | disclosed |
| CN-1331680-A | N-aryl (thio) anthranilic acid amide derivatives, their prepn. and their use as VEGF receptor tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2002-01-16 | — | — | CN | disclosed |