Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523495 | 0.99 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL27487730 | 0.92 | ITGB1 (0.39) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL27507489 | 0.91 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2POLBLMNA | |
| SCHEMBL27506254 | 0.91 | TAS1R3 (0.40) | TAS1R3TAS1R1TAS1R2ALDH1A1TSHR | |
| SCHEMBL27488441 | 0.91 | ESR1 (0.38) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL27507076 | 0.91 | ESR1 (0.38) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL28740748 | 0.91 | ESR1 (0.38) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL27487365 | 0.90 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2KDM4ENPSR1 | |
| SCHEMBL27489430 | 0.90 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL27506653 | 0.90 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1198831-C | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2005-04-27 | — | — | CN | disclosed |
| CN-1329005-A | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2002-01-02 | — | — | CN | disclosed |