SCHEMBL27487583

SCHEMBL27487583

CC(=O)OC1(CN)CC2CCCCC2C1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.30
HIF1A Q16665 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5038657 0.79 FUCA1 (0.32)
SCHEMBL28350691 0.79 FUCA1 (0.32)
SCHEMBL27484975 0.79 FUCA1 (0.32)
SCHEMBL10203740 0.78 EP300 (0.31) EP300HIF1ACREBBP
SCHEMBL8348448 0.77
SCHEMBL5042569 0.75 USP2 (0.36)
SCHEMBL10203320 0.75 EP300 (0.31) EP300HIF1ACREBBP
SCHEMBL2848937 0.75 CYP1A2 (0.42) EP300HIF1ACREBBP
SCHEMBL5042450 0.74 ALOX15 (0.35)
SCHEMBL27469787 0.74 ALOX15 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1165518-C Bicyclic amino acids as pharmaceutical agents ��ʲ 2004-09-08 CN disclosed
CN-1382118-A Bicyclic amino acids as pharmaceutical agents WARNER LAMBERT CO (US) 2002-11-27 CN disclosed