Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923759 | 0.89 | SMO (0.60) | HDAC6CMA1MEN1KMT2AEP300 | |
| SCHEMBL27488298 | 0.86 | CMA1 (0.59) | HDAC6CMA1MEN1KMT2AGSK3A | |
| SCHEMBL13793060 | 0.80 | HDAC6 (0.60) | HDAC6CMA1MEN1KMT2AEP300 | |
| SCHEMBL25409389 | 0.77 | CMA1 (0.58) | HDAC6CMA1MEN1KMT2AMMP1 | |
| SCHEMBL31528312 | 0.76 | KMT2A (0.56) | HDAC6CMA1MEN1KMT2ASIGMAR1 | |
| SCHEMBL13793149 | 0.74 | HDAC6 (0.52) | HDAC6CMA1MEN1KMT2AEP300 | |
| SCHEMBL22226690 | 0.74 | MMP1 (0.52) | HDAC6CMA1MEN1KMT2AMMP1 | |
| SCHEMBL15131567 | 0.74 | EP300 (0.60) | HDAC6CMA1MEN1KMT2AEP300 | |
| SCHEMBL17360678 | 0.73 | EHMT2 (0.61) | CMA1MEN1KMT2AMMP1MMP3 | |
| SCHEMBL14600666 | 0.72 | MEN1 (0.54) | HDAC6CMA1MEN1KMT2AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1178906-C | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ���Ͽع�����˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1261876-A | N-hydroxyformamide derivatives as inhibitors of matrix metalloproteinases | ABBOTT LAB (US) | 2000-08-02 | — | — | CN | disclosed |