⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723224 | 0.90 | — | — | |
| SCHEMBL105736 | 0.79 | — | — | |
| SCHEMBL104907 | 0.79 | — | — | |
| SCHEMBL2795828 | 0.71 | — | — | |
| SCHEMBL7697373 | 0.71 | — | — | |
| SCHEMBL132687 | 0.62 | — | — | |
| SCHEMBL1110010 | 0.60 | — | — | |
| SCHEMBL958835 | 0.59 | — | — | |
| SCHEMBL93125 | 0.55 | — | — | |
| SCHEMBL5310 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999956-B2 | N-[(het)arylalkyl)] pyrazole(thio)carboxamides and their heterosubstituted analogues | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-07 | — | — | US | claimed |
| EP-2576517-B1 | N-[(HET)ARYLALKYL)]PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER IP GMBH (DE) | 2014-12-17 | — | — | EP | claimed |
| EP-2576517-A1 | N-[(HET)ARYLALKYL)]PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | Bayer Cropscience AG (DE) | 2013-04-10 | — | — | EP | claimed |
| US-20130079302-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE(THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-28 | — | — | US | claimed |
| WO-2011151370-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | claimed |
| EP-2344449-A1 | ARYL-PHENYL-SULFONAMIDO-CYCLOALKYL COMPOUNDS AND THEIR USE | Pimco 2664 Limited (GB) | 2011-07-20 | — | — | EP | claimed |
| WO-2010032009-A1 | ARYL-PHENYL-SULFONAMIDO-CYCLOALKYL COMPOUNDS AND THEIR USE | PIMCO 2664 LIMITED (GB) | 2010-03-25 | — | — | WO | claimed |
| EP-1423467-A1 | FLUXING COMPOSITIONS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | claimed |
| US-20030111519-A1 | Fluxing compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-06-19 | — | — | US | claimed |
| WO-2003020816-A1 | FLUXING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-13 | — | — | WO | claimed |
| CN-114181205-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114478519-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117916215-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116472034-A | Indene compound, pharmaceutical composition thereof and therapeutic application thereof | 藤济(厦门)生物医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116063305-A | Macrocyclic compounds with BTK and/or RET activity and their use in medicine | 赛诺哈勃药业（成都）有限公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2003099858-A1 | CROSS-LINKED GLYCOPEPTIDE-CEPHALOSPORIN ANTIBIOTICS | THERAVANCE, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| US-20030130173-A1 | Cross-linked glycopeptide-cephalosporin antibiotics | THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC | 2003-07-10 | — | — | US | disclosed |
| US-20030111519-A1 | Fluxing compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2003031449-A2 | CROSS-LINKED GLYCOPEPTIDE-CEPHALOSPORIN ANTIBIOTICS | THERAVANCE, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| WO-2003020816-A1 | FLUXING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-13 | — | — | WO | disclosed |