Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489405 | 1.00 | PIM1 (0.50) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL19926359 | 0.95 | MAP4K4 (0.52) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL28307851 | 0.95 | MAP4K4 (0.52) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL5230710 | 0.91 | PIM1 (0.50) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL5232485 | 0.91 | PIM1 (0.50) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL5833254 | 0.91 | PIM1 (0.50) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL30783037 | 0.85 | CKS1B (0.47) | PIM1PIM3PIM2CTSKKDM4D | |
| SCHEMBL3212610 | 0.85 | CKS1B (0.47) | PIM1PIM3PIM2CTSKKDM4D | |
| SCHEMBL28180990 | 0.85 | PIM1 (0.48) | PIM1PIM3PIM2CTSKMAP4K4 | |
| SCHEMBL27546308 | 0.84 | PIM1 (0.49) | PIM1PIM3PIM2CTSKKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165534-C | Heterocyclyl amino methyloxazolidinones as antibacterials | — | 2004-09-08 | — | — | CN | disclosed |
| CN-1322203-A | Heterocyclic aminomethyl oxazolidinones as antibacterial agents | ASTRA ZENECA N V (SE) | 2001-11-14 | — | — | CN | disclosed |