Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.48 |
| ▸ | BTK | Q06187 | 5/20 | 0.47 |
| ▸ | JAK3 | P52333 | 3/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926359 | 1.00 | MAP4K4 (0.52) | MAP4K4F10AURKAPDPK1AURKB | |
| SCHEMBL27487705 | 0.95 | PIM1 (0.50) | MAP4K4F10BTKPIM1PIM3 | |
| SCHEMBL27489405 | 0.95 | PIM1 (0.50) | MAP4K4F10BTKPIM1PIM3 | |
| SCHEMBL5230710 | 0.86 | PIM1 (0.50) | MAP4K4F10BTKPIM1PIM3 | |
| SCHEMBL5833254 | 0.86 | PIM1 (0.50) | MAP4K4F10BTKPIM1PIM3 | |
| SCHEMBL5232485 | 0.86 | PIM1 (0.50) | MAP4K4F10BTKPIM1PIM3 | |
| SCHEMBL28566874 | 0.83 | HTT (0.54) | MAP4K4F10AURKAPDPK1AURKB | |
| SCHEMBL22608005 | 0.83 | MAP4K4 (0.48) | MAP4K4F10AURKAPDPK1AURKB | |
| SCHEMBL19926339 | 0.83 | MAP4K4 (0.48) | MAP4K4F10AURKAPDPK1AURKB | |
| SCHEMBL20354373 | 0.82 | MAP4K4 (0.57) | MAP4K4F10AURKAPDPK1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923107-A | The method for being used to prepare indole carboxamides compound | 百时美施贵宝公司 | 2019-06-21 | — | — | CN | disclosed |