SCHEMBL27488134

SCHEMBL27488134

c1ccc2c(c1)Cc1c(CSC3CCCCC3)cccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.53
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
KMT2A Q03164 1/20 0.35
HPGD P15428 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
MC4R P32245 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
QRFPR Q96P65 4/20 0.33
NR3C1 P04150 2/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2873915 0.78 PNMT (0.66) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL9225866 0.75 PNMT (0.50) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL9221121 0.74 PNMT (0.53) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL7195192 0.72 PNMT (0.72) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL5366733 0.72 PNMT (0.72) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL7607164 0.71 PNMT (0.70) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL7609046 0.71 PNMT (0.70) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL7606240 0.71 PNMT (0.70) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL7603814 0.71 PNMT (0.70) PNMTDRD2DRD4DRD3KMT2A
SCHEMBL9859906 0.71 PNMT (0.70) PNMTDRD2DRD4DRD3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1213079-C Solid catalyst composition for olefinic polymerization and catalyst thereof CHINA PETROCHEMICAL CORP (CN) 2005-08-03 CN claimed
CN-1508159-A Solid catalyst composition for olefinic polymerization and catalyst thereof 中国石油化工股份有限公司 2004-06-30 CN claimed
CN-1480453-A Compound of fluorene class containing dual hetero atoms as well as its synthetic method and application 中国石油化工股份有限公司 2004-03-10 CN claimed
CN-1267417-C Compound of fluorene class containing dual hetero atoms as well as its synthetic method and application CHINA PETROLEUM & CHEMICAL (CN) 2006-08-02 CN disclosed
CN-1213079-C Solid catalyst composition for olefinic polymerization and catalyst thereof CHINA PETROCHEMICAL CORP (CN) 2005-08-03 CN disclosed
CN-1508159-A Solid catalyst composition for olefinic polymerization and catalyst thereof 中国石油化工股份有限公司 2004-06-30 CN disclosed
CN-1480453-A Compound of fluorene class containing dual hetero atoms as well as its synthetic method and application 中国石油化工股份有限公司 2004-03-10 CN disclosed