Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983547 | 0.85 | KDM4E (0.63) | POLBKDM4ETP53GFERMEN1 | |
| SCHEMBL6982668 | 0.84 | POLB (0.60) | POLBKDM4ETP53GFERITGA4 | |
| SCHEMBL8403402 | 0.82 | GAA (0.55) | POLBKDM4ETP53GFERKMT2A | |
| SCHEMBL4772342 | 0.81 | POLB (0.62) | POLBKDM4ETP53GFERGRM5 | |
| Hydrochloric Acid SCHEMBL6980746 | 0.81 | POLB (0.61) | POLBKDM4ETP53GFERGRM5 | |
| SCHEMBL23244240 | 0.80 | ALDH1A1 (0.62) | POLBKDM4ETP53GFERMEN1 | |
| SCHEMBL23244242 | 0.80 | ALDH1A1 (0.62) | POLBKDM4ETP53GFERMEN1 | |
| SCHEMBL27146671 | 0.80 | HSD17B10 (0.66) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27146672 | 0.80 | HSD17B10 (0.66) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18049384 | 0.78 | POLB (0.52) | POLBKDM4EGFERITGA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1163145-A | Inhibiting agent for vascular formation | SENJI SEIYAKU K K (JP) | 1997-10-29 | — | — | CN | disclosed |