SCHEMBL27488222

SCHEMBL27488222

C=CC=Cc1ccc(C=CC=C(C)C=C)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.35
CYP3A4 P08684 3/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.31
EPAS1 Q99814 1/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.30
CYP2D6 P10635 1/20 0.30
KMT2A Q03164 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6518363 0.84 MAOB (0.50) CYP3A4MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL4471707 0.84 MAOB (0.50) CYP3A4MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL4359287 0.77 MAOB (0.52) APPCYP3A4ALDH1A1CYP2C19MAOB
SCHEMBL3967009 0.76 PTGS1 (0.40) CYP3A4MAPTKDM4EALDH1A1CYP2C19
SCHEMBL18407085 0.73
SCHEMBL20324359 0.73
SCHEMBL5599864 0.73
SCHEMBL4359280 0.72 CYP3A4 (0.51) CYP3A4MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL4359283 0.72 CYP3A4 (0.51) CYP3A4MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL6654702 0.72 NFE2L2 (0.50) CYP3A4MAPTKDM4ECYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1195672-A Process for preparing vulcanizable elastomeric compounds from granular elastomer blends and elastomeric articles manufactured therefrom UNION CARBIDE CHEM PLASTIC (US) 1998-10-14 CN disclosed