Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700638 | 0.93 | SRD5A2 (0.72) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL29773950 | 0.93 | SRD5A2 (0.72) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL14811372 | 0.89 | SRD5A2 (0.57) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL26187120 | 0.88 | MAOA (0.58) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL26187114 | 0.85 | SRD5A2 (0.61) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL29709873 | 0.84 | SRD5A2 (0.86) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL31069845 | 0.84 | SRD5A2 (0.86) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL3105349 | 0.84 | SRD5A2 (0.86) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL29773995 | 0.83 | NPC1 (0.64) | SRD5A2HTR2CHTR2BDRD2ADRA1D | |
| SCHEMBL28171211 | 0.82 | SRD5A2 (0.54) | SRD5A2HTR2CHTR2BDRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459068-B | Novel compositions, uses and processes for their preparation | 皮梅拉股份有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-106995443-A | New compositions, purposes and the method for preparing them | 皮梅拉股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106459068-A | Novel compositions, uses and processes for their preparation | 皮梅拉股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103073524-B | 4-[4-(substituted phenyl) piperazine piperazinyl-1]-butylcarbamic acid substituted aromatic ester derivative and preparation method thereof | NINGBO INST OF MICROCIRCULATION & HENBANE | 2015-06-10 | — | — | CN | disclosed |
| CN-103073524-A | 4-[4-(substituted phenyl) piperazine piperazinyl-1]-butylcarbamic acid substituted aromatic ester derivative and preparation method thereof | NINGBO INST OF MICROCIRCULATION & HENBANE | 2013-05-01 | — | — | CN | disclosed |
| CN-101213190-A | Compounds and compositions useful as TPO mimetics | IRM LLC (BM) | 2008-07-02 | — | — | CN | disclosed |
| CN-1161334-C | Nitrogen-containing tetracyclic compounds | ������ҩ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1280567-A | Nitrogen-containing tetracyclic compounds | TAISHO PHARMACEUTICAL CO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |