Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474291 | 0.77 | TSHR (0.48) | TSHR | |
| SCHEMBL27507067 | 0.70 | GABRP (0.33) | — | |
| SCHEMBL4696447 | 0.67 | NQO2 (0.44) | — | |
| SCHEMBL4037355 | 0.66 | NQO2 (0.40) | TSHR | |
| SCHEMBL28340647 | 0.65 | TSHR (0.54) | TSHR | |
| SCHEMBL96485 | 0.63 | — | — | |
| SCHEMBL27487327 | 0.61 | GABRP (0.61) | — | |
| SCHEMBL6360346 | 0.61 | MAPT (0.46) | — | |
| SCHEMBL3750742 | 0.61 | MAPT (0.46) | — | |
| SCHEMBL4642161 | 0.60 | MEN1 (0.43) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1210267-C | 2-hydroxy-mutilin carbamate derivatives for antibacterial use | SMITHKLINE BEECHAM PLC (GB) | 2005-07-13 | — | — | CN | disclosed |
| CN-1427827-A | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use | SMITHKLINE BEECHAM PLC (GB) | 2003-07-02 | — | — | CN | disclosed |