Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939408 | 0.90 | LTB4R2 (0.41) | ALDH1A1MAPTMAPK1LTB4R2LMNA | |
| SCHEMBL27847370 | 0.84 | PTPN1 (0.34) | ALDH1A1MAPTLTB4R2LMNAPDCD1 | |
| SCHEMBL7771116 | 0.84 | LTB4R2 (0.42) | ALDH1A1LTB4R2LMNAPTPN1 | |
| SCHEMBL7015019 | 0.81 | LTB4R2 (0.44) | ALDH1A1MAPTMAPK1LTB4R2LMNA | |
| SCHEMBL8566901 | 0.76 | LTB4R2 (0.42) | ALDH1A1MAPTLTB4R2LMNASMN1; SMN2 | |
| SCHEMBL9586936 | 0.76 | FNTA (0.39) | ALDH1A1MAPTMAPK1LTB4R2LMNA | |
| SCHEMBL6849336 | 0.75 | AGTR1 (0.39) | ALDH1A1MAPTMAPK1LTB4R2LMNA | |
| SCHEMBL27862729 | 0.75 | NR1H4 (0.39) | ALDH1A1MAPTLTB4R2LMNAPDCD1 | |
| SCHEMBL9586285 | 0.75 | FNTA (0.39) | ALDH1A1MAPTMAPK1LTB4R2SMN1; SMN2 | |
| SCHEMBL9586519 | 0.75 | FNTA (0.40) | ALDH1A1MAPTLTB4R2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497300-C | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-06-10 | — | — | CN | claimed |
| CN-1203223-A | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-30 | — | — | CN | claimed |
| CN-100497300-C | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1203223-A | Production method of aminobenzene compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-30 | — | — | CN | disclosed |