Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 12/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 12/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470043 | 0.79 | CDC7 (0.53) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL7834057 | 0.79 | CDC7 (0.59) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL27487825 | 0.73 | AKT2 (0.38) | CDC7DBF4HSD17B10TP53LMNA | |
| SCHEMBL31060605 | 0.72 | CDC7 (0.73) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL7832613 | 0.71 | CDC7 (0.53) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL796398 | 0.71 | CDC7 (0.72) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL27739109 | 0.69 | CDC7 (1.00) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL7832610 | 0.68 | CDC7 (0.54) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL31606731 | 0.65 | G6PD (1.00) | CDC7DBF4G6PDHSD17B10TP53 | |
| SCHEMBL2888994 | 0.65 | G6PD (1.00) | CDC7DBF4G6PDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168138-A | Aryl and heteroaryl purine compounds | PHARMACIA & UPJOHN SPA (IT) | 1997-12-17 | — | — | CN | claimed |
| CN-1168138-A | Aryl and heteroaryl purine compounds | PHARMACIA & UPJOHN SPA (IT) | 1997-12-17 | — | — | CN | disclosed |