Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042001 | 0.91 | REN (0.75) | REN | |
| Tert-Butyl Formate SCHEMBL27502160 | 0.89 | REN (0.67) | REN | |
| Tert-Butyl Formate SCHEMBL27555325 | 0.88 | REN (0.66) | REN | |
| Tert-Butyl Formate SCHEMBL27502529 | 0.88 | REN (0.71) | REN | |
| Tert-Butyl Formate SCHEMBL27512975 | 0.88 | REN (0.70) | REN | |
| Tert-Butyl Formate SCHEMBL27487146 | 0.87 | REN (0.63) | REN | |
| Tert-Butyl Formate SCHEMBL27555330 | 0.87 | REN (0.65) | REN | |
| Tert-Butyl Formate SCHEMBL27488918 | 0.87 | REN (0.65) | REN | |
| Tert-Butyl Formate SCHEMBL27503270 | 0.85 | REN (0.70) | REN | |
| Tert-Butyl Formate SCHEMBL27488921 | 0.83 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |