Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28134422 | 0.90 | PDPK1 (0.39) | TSHRPDPK1CYP2A6TRPA1ALDH1A1 | |
| SCHEMBL28811 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4776707 | 0.85 | — | — | |
| SCHEMBL28295847 | 0.85 | — | — | |
| Water SCHEMBL27898216 | 0.85 | — | — | |
| SCHEMBL506408 | 0.85 | — | — | |
| Phenol SCHEMBL2774765 | 0.79 | RIOK2 (0.43) | TSHRTDP1PDPK1TRPA1ALDH1A1 | |
| Nitrobenzene SCHEMBL28146083 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| Piperidine SCHEMBL28173675 | 0.72 | CYP2D6 (0.33) | TSHRALDH1A1HSD17B10NOS1 | |
| Pyridine SCHEMBL28371237 | 0.72 | PDPK1 (0.58) | TSHRNAPRTTDP1PDPK1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822163-B | Crth2 modulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2016-01-20 | — | — | CN | disclosed |
| CN-102084250-B | Compositions and methods for detecting a target response and treating a flavivirus infection symptom | ACADEMIA SINICA | 2014-08-06 | — | — | CN | disclosed |
| CN-102414168-B | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists | ACTELION PHARMACEUTICALS LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-102822163-A | Crth2 modulators | IRONWOOD PHARMACEUTICALS INC | 2012-12-12 | — | — | CN | disclosed |
| CN-102414168-A | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists | ACTELION PHARMACEUTICALS LTD | 2012-04-11 | — | — | CN | disclosed |
| CN-102084250-A | Compositions and methods for detecting a target response and treating a flavivirus infection symptom | ACADEMIA SINICA | 2011-06-01 | — | — | CN | disclosed |
| CN-1166654-C | Benzoylguanidine derivatives with advantageous properties, method for producing them and their use in production of medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-09-15 | — | — | CN | disclosed |
| CN-1342153-A | Benzoylguanidine derivatives having advantageous properties, method for the production thereof and use thereof for producing medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-03-27 | — | — | CN | disclosed |