Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 13/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27469590 | 0.89 | PTGS2 (0.58) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27489275 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27487892 | 0.89 | PTGS2 (0.48) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27487170 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27487165 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1SMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL4191401 | 0.83 | PTGS2 (0.85) | PTGS2PTGS1 | |
| SCHEMBL27472003 | 0.82 | PTGS2 (0.48) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27488240 | 0.81 | PTGS2 (0.45) | PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL27486811 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1PKMMITFHTT | |
| SCHEMBL27489267 | 0.80 | PTGS2 (0.59) | PTGS2PTGS1SMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |